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Reversible cerebral vasoconstriction syndrome
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Reversible cerebral vasoconstriction syndrome : ウィキペディア英語版
Reversible cerebral vasoconstriction syndrome

Reversible cerebral vasoconstriction syndrome (RCVS, sometimes called Call-Fleming syndrome) is a disease characterized by a weeks-long course of thunderclap headaches, sometimes focal neurologic signs, and occasionally seizures.〔 Symptoms are thought to arise from transient abnormalities in the blood vessels of the brain.〔 In some cases, it may be associated with childbirth, vasoactive or illicit drug use, or complications of pregnancy.〔
For the vast majority of patients, all symptoms disappear on their own within three weeks.〔 Deficits persist in a small minority of patients, with severe complications or death being very rare.〔 Because symptoms resemble a variety of life-threatening conditions, differential diagnosis is necessary.〔
==Characteristics==
The key symptom of RCVS is recurrent thunderclap headaches, which over 95% of patients experience. In two-thirds of cases, it is the only symptom.〔 These headaches are typically bilateral, very severe and peak in intensity within a minute.〔 They may last from minutes to days, and may be accompanied by nausea, photophobia, phonophobia or vomiting.〔 Some patients experience only one headache, but on average there are four attacks over a period of one to four weeks.〔 A milder, residual headache persists between severe attacks for half of patients.〔
1–17% of patients experience seizures. 8–43% of patients show neurologic problems, especially visual disturbances, but also hemiplegia, ataxia, dysarthria, aphasia, and numbness.〔 These neurologic issues typically disappear within minutes or a few hours; more persistent symptoms may indicate a stroke.〔 Posterior reversible encephalopathy syndrome is present in a small minority of patients.
This condition features the unique property that the patient's cerebral arteries can spontaneously constrict and relax back and forth over a period of time without intervention and without clinical findings. Vasospasm is common post subarachnoid hemorrhage and cerebral aneurysm, but in RCVS only 25% of patients have symptoms post subarachnoid hemorrhage.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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